| Both the (shown) immunophenotype (CD33+, HLA-DR-) and the karyotype t(15;17) are typical in APL.[1] |
Blasts with rare granules and an Auer rod in the central cell. Nuclei have bizarre convolutions resembling "monoblasts." These abnormal cells lack the characteristic heavy granulation typical in APL. Because of their hyperbasophilic cytoplasm and convoluted nuclei, this subtype can be easily confused with a monocytoid form of AML.[1] |
