AML Atlas, Facts & Trends: M6

Acute erythroleukemia (M6)

"At present, the prognosis (as reflected in survival) is relatively good for [AML] patients with rearrangements of 16q22, with the t(8;21) (q22;q22), and normal findings, whereas those with 11q23 abnormalities or 7q-/-7 have a poor prognosis."^[7]

Megaloblastic erythroid precursors, an abnormal mitotic figure, and one myeloblast.

Complex karyotypes as shown are often hypodiploid and include abnormal markers and ring chromosomes common in M6.