Immunotherapy may be the next great hope for cancer treatment. While monoclonal antibodies, cytokines, and vaccines have individually shown some promise, it is likely that our best strategy to combat cancer will be to attack on all fronts. Clearly, different strategies demonstrate benefit in different patient populations. It may be that the best results are obtained with vaccines in combination with a variety of antigens, or vaccine and antibody combinations. Nonspecific and specific immunotherapy combinations may be another potent strategy. The effect of any of the aforementioned strategies in combination with more traditional cancer therapies is another avenue, as we have seen some benefit in terms of duration with cytokines and chemotherapy.

Through these concerted efforts, our ultimate achievable goal may be a durable anti-tumor immune response that can be maintained over the course of a patient's lifespan.

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