M301 Dr. Wright: These patients are clearly at risk with Hepatitis B cirrhosis of developing liver cancer and that risk may be life long as high as 10 to 15 percent. The way we screen these patients however is controversial because our current screening tests are not very sensitive. Even at high resolution CT scans can miss lesions that are one centimeter in diameter and ultrasounds are probably less sensitive.... Increasingly, we're performing CT scans to screen for hepatocellular carcinoma, although CT scans are more expensive than performing ultrasounds and they also carry within a low risk of radiation of nephrotoxicity from the intravenous contrast.