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Camptosar

Treatment Options
rule

Camptosar Injection is indicated for the treatment of patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following 5-FU-based therapy.

Weekly Dosage Schedule
weekly graph

Starting Dose in Compromised Patients

  • Combined history of prior pelvic/abdominal irradiation and modestly elevated baseline serum total bilirubin levels (1.0-2.0 mg/dL): Consider starting at 100 mg/m2
  • Baseline serum total bilirubin levels > 2 mg/dL: No recommendation available at this time.

 

Once-Every-3-Week Dosage Schedule
3 week graph

Starting Dose in Compromised Patients

  • Age 70: Start at 300 mg/m2
  • Performance Status 2: Start at 300 mg/m2
  • Prior pelvic/abdominal irradiation: Start at 300 mg/m2
  • Baseline serum total bilirubin levels > 2 mg/dL: No recommendation available at this time.

 

Recommended Dose Modifications for the Weekly and Once-Every-3-Week Schedulesa

A new course of therapy should not begin until the granulocyte count has recovered to 1500/mm3, and the platelet count has recovered to 100,000/mm3, and treatment-related diarrhea is fully resolved. Treatment should be delayed 1 to 2 weeks to allow for recovery from treatment-related toxicities. If the patient has not recovered after a 2-week delay, consideration should be given to discontinuing Camptosar.

modification table

Please see full prescribing information.

 

Camptosar


Pharmacia & Upjohn Yakult Daiichi

© 1998 Pharmacia & Upjohn Company

USX 2288.00 December 1998

Immodium A-D is a registered trademark of
Janssen/McNeil Consumer Products

 

Full Prescribing Information ]

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