To Beav, Marty, tarnknight and anyone else interested in MGN-3.
Here is the shortest and best summary I've seen of the clinical
research on MGN-3. I'm not sure how you define
It costs $1 per pill. Recommended dosages are 12 per day for
about 2 weeks for people with diagnosed cancer. Gradually
the next 6 weeks, the recommended dosage reduces to 4 per day.
Each capsule is 250 mg. One of the immune system tests which
Marty referred to is the "51 Chromium release assay"
is mentioned in the following report. I will also include, if
my fingers don't give out, a letter from the discoverer of MGN-3,
Dr. Ghoneum, with his advice on this compound. I have
no financial interest in MGN-3 or any other product.
You can order it by calling CompassionNet at (800) 510-2010.
To your health!
MUSHROOM AMMUNITION copyright Alternative Medicine Digest, May 1999
Dr. Mamdooh Ghoneum of Charles Drew University of Medicine and
Science in Los Angeles compares current cancer treatment to
battling terrorists. By bombing a city, you can kill most
terrorists, although innocent civilians will also be killed.
"Chemotherapy, radiation or surgery are the cancer-equivalents
of bombing," he says, "and the beneficial white blood cells
the area are non-terrorist victims."
Even after bombing, however, some terrorists may survive, as
do those cancer cells that are resistant to the usual therapies.
Rather than bombing the city again, however, Dr. Ghoneum advocates
sending in Special Forces to locate and eliminate the remaining
terrorists one by one.
Dr. Ghoneum's development of a natural supplement called MGN-3 is
meant to arm the body's Natural Killer cells to seek and destroy
dangerous invaders one by one.
The human immune system is comprised of more than 130 subsets of
white blood cells. About 15% of them are called Natural
(NK) cells. These provide the first line of defense for
with any form of invasion to the body. Each cell contains
small granules which act as "ammunition." When an NK cell
a cancer cell, for instance, it attaches itself to the cell's outer
membrane and injects these granules directly into the interior of
The granules then "explode," destroying the cancer cells within
minutes. The killer cell then moves on to other cancer cells
repeats the process. As long as NK cells remain active, the
is able to keep disease under control.
The supplement developed by Dr. Ghoneum, called MGN-3, increases
efficacy of the NK cells. Additionally, it has other
effects as well: it increases levels of interferon, a compound
duced by the body that inhibits the replication of viruses; it
increases the formation of Tumor Necrosis Factors, a group of
that help destroy cancer cells; and it increases the activity of T-
cells and B-cells. This potent immune system booster is made of
outer shell of rice bran which has been enzymatically treated with
extracts from the medicinal Shiitake mushroom. In Japan,
extracts have become the leading prescription treatments for
Dr. Ghoneum's findings have been demonstrated in test-tube
as well as seven published studies involving 72 patients. In a
presented to the American Association for Cancer Research, he
on five patients with breast cancer. Each patient was treated
the same dosage of three grams a day of MGN-3 from a Japanese manu-
facturer. NK cell activity increased within two weeks and
to do so as the study progressed. At the end of the
month study, two of the patients were in complete remission. In
study reported the following year, 27 patients with various types
of cancers including breast, cervical, prostate, leukemia and
myeloma were tested for NK cell activity by 51 Chromium release
before and after only two weeks treatment with MGN-3.
NK cell activity increased 154-332% for breast carcinoma, 100-274%
cervical cancer, 174-385% in prostatic cancer, 100-240% in leukemia
and 100-537% in multiple myeloma.
One multiple myeloma patient was a 58-year-old man diagnosed in
He underwent several months of chemotherapy following his
Although his condition seemed to stabilize, his blood still showed
markers for multiple myeloma eight months after chemotherapy.
He then began taking MGN-3 and in less than 6 months, follow-up lab
work showed no indication of cancer. Today, eight years after
initial diagnosis, he is the first patient known to have survived
multiple myeloma, acccording to Dr. Ghoneum.
Dr. Warren Levin, 66, a holistic physician practicing in New York
City and Ridgefield, Connecticut, had suffered an immune deficiency
with an abnormal ratio of helper cells to suppressor cells since
early '80s. "I tried herbs, healers, intravenous
sorts of stuff. Several years ago, I learned about
carbohydrate molecules that play a critically important role in
to-cell communication. I began looking for glyconutrient
All over the world, native populations were using substances with
high glyconutrient content including Aloe Vera, astralagus,
and various mushrooms. At that point, I read an article about
I was already taking Coats Aloe Vera Concentrate together with Beta
1-3, D-glucan (Macroforce), Ambrotose, and a thymus preparation
Basic Thymic Protein A as well as the usual vitamins, minerals and
antioxidants. I also did intensive mercury detoxification with
Last fall, I began taking six capsules a day of MGN-3. At the end
December, I sent my blood to the laboratory and when I returned
vacation I found that for the first time in 15 years, every one of
my tests had improved well into the middle range of normalcy.
combination of supplements had finally reversed my helper-cell
And normalized my mitogen/allergen responses and NK cell
Dr. Ghoneum's latest study, reported in the International Journal
Immunotherapy, involved 24 patients. Doctors tested NK cell
in each patient, administered the recommended cancer dosage of 3
per day, and tested NK cell activity again after 16 hours, one
one month and two months. After 16 hours NK cell activity had
1.3 to 1.5 times. After one week, activity had increased
the end of two months, NK cells were killing 27 times more cancer
than prior to taking MGN-3.
Unlike other forms of cancer treatment, MGN-3 is a totally harmless
stance and has no known side effects. In the terrorist analogy, it
doesn't kill innocent civilians. David A. Pitts, 73, a real
salesman in Santa Barbara, California, had undergone chemotherapy
lymphoma with no apparent results. "I had been getting weaker
weaker," he said. After reding a report on MGN-3, he sent for
supplement and began taking it while he was also placed on a course
of intravenous treatment with trioxine, a relatively new drug.
about three to four weeks on the outside, gosh, I started feeling
better," says Pitts. "What really intrigued me was the
this supplement could enhance your immune system. When I began, I
did a crash program of 14 capsules a day. Now I'm on a preventative
program of four a day." At his latest CAT-scan, Pitts was in
"The doctor had no explanation of how or why this happened, and
nothing I can prove. But I'm going to continue taking this for the
rest of my life. What's in it is harmless and doesn't interfere
Dr. Ghoneum has also used MGN-3 to treat hepatitis B and C and has
done in vitro experiments demonstrating its action against HIV.
that individuals in "high risk" categories for disease can
using MGN-3 preventatively. These include:
Individuals, such as artists and house painters, who
work with paint.
Those born with immune deficiencies.
Families with a strong history of cancer.
Chemical and refinery workers.
End of Alternative Medicine Digest article.
My fingers are getting tired. I decided to test my high school
typing expertise to get this article in a form where you can send
to others by e-mail, print it out to study it or have your loved
read it....or ignore it. Your choice. I've always told my
the most useful thing I ever learned in school was touch typing.
OK, here's the letter I promised you from Dr. Mamdooh Ghoneum, the
discoverer of MGN-3:
As a research scientist studying immune system function, I have
my entire career investigating promising therapies for
immune response, with special attention to the functioning of key
blood cells (NK cells, T cells and B cells).
Of all the promising approaches I have investigated, MGN-3, with
extraordinary effect on NK cell activity, is far and away the most
exciting. So great is its promise, in fact, that I have
all other research to concentrate all my attention on MGN-3.
You should be aware, however, that this is my opinion, and not all
medical experts agree with me. Many doctors, having read my
are encouraging their patients to supplement with MGN-3. Many
however, view my research with a healthy skepticism. You should
aware that there are a significant number of experts that do not
believe that sufficient scientific evidence exists to support the
use of alternative therapies, of which MGN-3 is one. Others are
concerned that patients using products like MGN-3 may abandon their
traditional medical treatment - something I do not want to
Certainly your personal physician, who knows your health history,
be involved in your decision on whether supplementing with MGN-3 is
good idea for you. That is why I encourage you to share the
abstracts from the clinical research with your doctor, or other
care provider, before you decide to start supplementing with MGN-3.
also encourage you to seek out other sources of information on
supplements in general, and other specific concerns you might have,
agencies such as the United States Food and Drug Administration,
can be easily accessed on the Internet at: www.fda.gov
As you review the information in this package, please remember that
colleagues and I have been studying the effects of MGN-3 on immune
response. Much more work is needed to better understand where thes
will bring us. And please do not forget that MGN-3 is a dietary
designed to support optimal immune system function - not a medical
preventative, or cure for any health condition.
For purposes of full disclosure: I receive research support from
Pharmaceutical Co. in Japan and research/financial support from Lane
Labs-USA, Inc. based on MGN-3 sales.
My best wishes for your continued good health,
Mamdooh Ghoneum, Ph.D."
The "abstracts" of the clinical studies which Dr. Ghoneum
refers to may be
obtained by calling CompassionNet at the above "800"