[MOL] CONCLUSION ON RARE EYE MELANOMA: DON'T TOUCH [01165] Medicine On Line


[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]

[MOL] CONCLUSION ON RARE EYE MELANOMA: DON'T TOUCH



Good Morning My Friends,

Once again, i am hoping these articles are beneficial for those that are
seeking the answers to good health.

CONCLUSION ON RARE EYE MELANOMA: DON'T TOUCH
-------------------------------------------------------------------
PHILADELPHIA--About a quarter of patients with conjunctival melanoma 
relapse within five years.

So found the second-largest series of this rare tumor ever collected, 
a study of 150 consecutive patients over 23 years with 254 melanomas 
followed for an average of seven years.

Melanomas not touching the limbus and involvement of the lateral 
margin were related to relapse and metastasis, Dr.Carol Shields and 
colleagues of the Wills Eye Hospital here reported. Their study was 
an effort to determine the characteristics of conjunctival melanoma 
and factors related to unfavorable outcomes.

The researchers concluded that the type of initial surgery could
possibly prevent tumor recurrence, metastasis, and death. They suggest 
using a "no-touch" technique and wide microsurgical excisional 
biopsy, cryotherapy, and alcohol epitheliectomy. They recommend that
incisional biopsy be avoided.

Fifty-two of the patients (35%) had a recurrence, the Wills group
reported in the November Archives of Ophthalmology. Of the 52
patients, 28 (19%) relapsed once, 11 (7%) twice, five (3%) three 
times, three (2%) four times, and five (3%) five times or more.

After five years of follow-up 26% of the patients had relapsed, at 
10 years it was 51%, and at 15 years it was 65%. Average time from 
first to second recurrence was 15 months.

Twenty-seven patients (18%) developed metastases. Seventeen were 
in lymph nodes, two in the lung, four in the brain, three in the 
liver, and one disseminated. Metastases were identified 
in 16% of the patients at five years, 26% by 10 years, and 32% by 15 
years. Twelve patients (8%) died from the disease.


God Bless YOu,
marty auslander
------------------------------------------------------------------------
This is an automatically-generated notice.  If you'd like to be removed
from the mailing list, please visit the Medicine-On-Line Discussion Forum
at <http://www.meds.com/con_faq.html>, or send an email message to:
majordomo@lists.meds.com
with the subject line blank and the body of the message containing the line:
unsubscribe mol-cancer your-email-address
where the phrase your-email-address is replaced with your actual email
address.
------------------------------------------------------------------------