[MOL] Arimidex Highly Effective For Advanced Breast Cancer [01721] Medicine On Line


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[MOL] Arimidex Highly Effective For Advanced Breast Cancer



 Arimidex (Anastrozole) First-Line Therapy Highly Effective
    For Advanced Breast Cancer
    [09/28/2000; Doctor's Guide]

BRUSSELS, BELGIUM -- September 28, 2000 -- Results from two studies
released at the second annual European Breast Cancer Conference
in Brussels confirm Arimidex (anastrozole) as a first choice,
first-line therapy for postmenopausal women with hormone-receptor
positive advanced breast cancer.

New data provides physicians with the additional reassurance that
using Arimidex first-line does not compromise tamoxifen's efficacy
when it is used subsequently as second-line treatment.

The study's findings, released just prior to the beginning of
National Breast Cancer Awareness Month in Canada, are especially
encouraging for women living with the disease. Breast cancer
is currently the leading cause of death among Canadian women
between the ages of 35 and 55. It is estimated that 19,200 women
will develop breast cancer this year in Canada and 5,500 are
expected to die from the disease in 2000.

A prospective combined analysis of 1021 patients from two randomized,
double blind trials of identical design, compared the efficacy
and tolerability of Arimidex (1mg daily) with tamoxifen (20mg
daily) when used as first-line therapy in postmenopausal women
with advanced breast cancer. Primary endpoints were time to progression
(TTP), objective response and tolerability.

The full article can be found at:

http://www.docguide.com/dgc.nsf/news/0F919DC717168FDA852569680063A090

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