[MOL] Implantable drug pump approved for pain and colorectal liver cance [01442] Medicine On Line

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[MOL] Implantable drug pump approved for pain and colorectal liver cancer...

Tuesday, July 25, 2000
Medtronic implantable drug pump approved by FDA

MINNEAPOLIS, Jul 25 (Reuters) - Medical device maker Medtronic Inc. said on Tuesday its implantable drug pump was approved by the US Food and Drug Administration for use in treating colorectal liver cancer and chronic pain.

The IsoMed Constant-Flow Infusion System is used to deliver cancer-fighting medication directly to the liver, which is the most common place for colon cancer to spread.

It also can deliver morphine sulphate directly into the spinal fluid as a treatment for pain.

In treating patients with colorectal cancer that has spread to the liver, Medtronic's device pumps high concentrations of floxuridine (FUDR) on a continuous basis to the liver through the hepatic artery, the main blood supply for liver tumors, Medtronic said.

The IsoMed drug pump is surgically placed under the skin of the abdomen and filled with the appropriate medication. A catheter that runs from the pump to the hepatic artery delivers medication at a constant rate from the pump into the liver.

In June, Minneapolis-based Medtronic won FDA-approval of its implantable cardioverter defibrillator used to detect and treat arrhythmia, or irregular beating, of both the upper and lower chambers of the heart.

Shares of Medtronic closed Monday at 52-5/16, just off a year high of 57-and up from a low of 29-15/16.


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