Re: [MOL] Questions about lasting effects of chemotherapy/Reply [00273] Medicine On Line

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Re: [MOL] Questions about lasting effects of chemotherapy/Reply

Dear Chris:  I have included information to help you understand what is happening.  Chemo builds up in the body and therefore can also take some time to completely leave the body.  I have heard of people on Taxol having flu like symptoms.  I was very happy to hear that your father has gone five year's, that is great.  Also that his platelets are good, gosh that is great.  Welcome to our forum, warmly, your friend, lillian


Certain drugs, if leaking, can cause severe damage to the skin and the underlying tissues. Among them are:

  • Adriamycin
  • BiCNU
  • Carboplatinum
  • Daunorubicin
  • DTIC
  • Fludarabine
  • Gemcitabine
  • Idarubicin
  • Irinotecan
  • Mithramycin
  • Mitomycin
  • Mitoxantrone
  • Navelbine
  • Nitrogen Mustard
  • Taxol
  • Taxotere
  • Topotecan
  • Velban
  • Vincristine
  • VP-16

Drug: Ondansetron, Zofran

Zofran is used to prevent or minimize nausea and vomiting caused by cancer chemotherapy, radiation therapy, anesthesia, and surgery

Before taking Zofran:

  • Inform your physician if you have or have ever had liver disease.
  • Inform your physician and pharmacist if you are allergic to Zofran or any other drugs.
  • Inform your physician if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Zofran, notify your physician.
  • As with any new medication, tell your physician and pharmacist what prescription and nonprescription medications you are taking, including vitamins.

What SIDE EFFECTS can this medicine cause?
Although side effects from Zofran are not common, they can occur. If you experience any of the following symptoms, call your doctor immediately:

  • Chest pain, irregular heartbeat or difficulty breathing
  • Fainting
  • Headache
  • Dizziness, weakness or drowsiness
  • Stomach pain, constipation or diarrhea

Drug: Taxol, Paclitaxel

Warnings and precautions:
This drug can cause a decrease in the number of all types of blood cells in your bone marrow. Your doctor will monitor your blood values before, during, and after your treatment .Do not have any vaccinations such as measles or flu shots without talking to your physician.

Taxol can cause liver damage. Before taking this drug tell your physician:

  • If you are allergic to this or any other drugs.
  • What prescription and nonprescription medications you are taking, especially aspirin and vitamins.
  • If you have or have ever had heart, kidney, or liver disease.

You should not plan to have children while receiving chemotherapy or for a specified period of time after treatments. Discuss the risks of pregnancy or conception before and after chemotherapy with your physician. This drug may interfere with the normal menstrual cycle in women and may affect or stop sperm production in men. Do not assume that you are not capable of becoming pregnant or that you cannot impregnate someone else. Pregnant women or women who are breast-feeding should tell their doctors before taking this drug. Use a reliable method of birth control to prevent pregnancy. This drug may harm the fetus.

A reaction may occur during the administration of this medication. Prior to treatment you should receive medication to help prevent these reactions. With the use of these preventive medications, the allergic reactions are uncommon or lessened. Your nurse or physician will monitor you carefully during the infusion to treat these effects if they occur.

Diseases commonly treated with this drug:

  • Metastatic breast cancer
  • Metastatic ovarian cancer
  • Non-small cell lung cancer
  • Small cell lung cancer,
  • Head and neck cancer
  • Bladder cancer
  • Kaposi's sarcoma
  • Prostate cancer

Side effects from this drug are common and include:

  • Thinned or brittle hair
  • Loss of appetite or weight

Contact your doctor if any of these symptoms are severe or persist for several hours:

  • Nausea and vomiting
  • Stomach pain
  • Diarrhea
  • Constipation
  • Changes in taste
  • Mouth blistering
  • Changes in vision
  • Fatigue

Call your doctor immediately if you experience any of the following symptoms:

  • Numbness or tingling or pain
  • Fever or chills
  • Cough
  • Sore throat
  • Difficulty swallowing
  • Shortness of breath or wheezing
  • Swelling of the lower extremities such as feet or ankles or other body parts
  • Weight gain or overall puffiness
  • Red or reddish colored urine
  • Unusual bruising or bleeding
  • Black, tarry stools
  • Feeling of faintness or dizziness
  • Facial flushing
  • Chest pain
  • Back pain or pain in your side
  • Rash
  • Dizziness
  • Muscle aches and other flu-like symptoms
  • Bone pain
  • Severe vomiting
  • Change in normal bowel habits for more than 2 days
We invite you to take a look at our Album.                                      
  ( Very informational, good tips, Molers pictures, art work and much more....
----- Original Message -----
From: Chris Greene
Sent: Monday, June 05, 2000 4:13 PM
Subject: [MOL] Questions about lasting effects of chemotherapy

I need to know if anyone has experienced the same effects as my Dad
(aged 75) who is going through chemotherapy for small cell lung cancer.
My father has only one lobe of one lung left.  He has survived for five years
by having pieces of his lungs surgically removed and then he had chemo.
He has not needed to be on oxygen and even now his doctors say he doesn't need to be on oxygen. He tolerated all this very well even the chemo until this last treatment.
Three weeks ago, he was treated with  Taxol 100mg, Zofran 2mg, Dexamethosone 4 mg, Zantac 25mg and Paraplation 50mg and 150mg.
Ever since he has had chills and hot flashes, feels weak with flu like symptoms, the skin on his hands blistered and peeled all off.  His oncologist says the chemicals can't be causing these continuous symptoms.  Theye checked for an infrection in the blood and none was found. White counts and othet counts are ok.  
Does anyone have any ideas on what a cause and or treatment for this can be?  We are desperate for some help .  Thanks