There are many angiogenesis drugs that work similarly to endostatin (the
newest which has thus far only been tried on mice) which is scheduled to be
tried in Phase I (this tests toxicity) and is only desirable as a last
resort. It will be offered at Harvard, Anderson in Houston and Madison
Wisconsin (check the NIH trials site). I already called all three places for
my husband who has inoperable late stage lung cancer. They will be taking
about 15-25 people in each place and have had almost 1,000 inquiries. It
will be decided strictly by committees in all places and they are setting up
strict criteria now. For example, only solid tumors, etc. Sorry to be so
negative, but I think it will be REALLY hard to get into Phase I of this
trial. PS If you go to the Medscape site and check the presentations of the
three day annual oncology conference for this past April, there's a
discussion of the possible risks of this kind of drug as well. Anyhow, good
luck. We're in the same boat and my sister has very bad esophagal cancer
too. So much for cheery news.
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