Thanks Barb, I put this over the Mol line yesterday, love you, lillian
----- Original Message -----
From: Barbara Silverman <silverb@warwick.net>
To: <RWolf111@aol.com>; <mol-cancer@lists.meds.com>;
<fitecancer@earthlink.net>; <firefly@islc.net>; <joicy@erols.com>;
<lehnerj1@juno.com>; <blessu@worldnet.att.net>
Sent: Tuesday, August 03, 1999 9:43 PM
Subject: (no subject)
> Thought you might like a copy of the MMSK newsletter. Please notice
> that there is an online chat about trials tomorrow evening from 8 to 9.
> The URL is down below.
>
> Love,
> Barbara
>
>
>
>
> Subject:
> Lately@MSKCC
> Date:
> Mon, 2 Aug 1999 17:19:41 -0500
> From:
> lately@mskcc.org
> To:
> silverb@warwick.net
>
>
> Lately@MSKCC
> --------------------
> What's new at
> Memorial Sloan-Kettering Cancer Center
> and its World Wide Web Site
> ---------------------
> http://www.mskcc.org
> ====================================================
> August, 1999
>
> Welcome to Lately@MSKCC!
>
> In this issue
>
> -Pain research
>
> -Clinical trials live chat
>
> -Advances in breast-cancer treatment
>
> Pain is one of the most feared aspects of cancer, and the
> control of pain is a key mission for the physicians and
> researchers at Memorial Sloan-Kettering Cancer Center.
> Recently, researchers here have made crucial discoveries
> about the genetics of receptors on cell surfaces that are
> involved in triggering morphine's pain-controlling effects.
> These discoveries could lead to better pain treatment with
> fewer side effects, and they may also provide a clue to
> treating drug addiction.
>
> Dr. Gavril W. Pasternak and his colleagues are zeroing in on
> "mu" receptors, the places on cell surfaces to which morphine
> and other opiates bind. Early studies of morphine showed that
> its actions vary depending on which types of mu receptors its
> molecules bind to. The specific type of receptor dictates
> what the drug does. For example, when a morphine molecule
> bonds to one type of mu receptor, it will dull pain. But when
> it binds to another type of mu receptor, it might have a
> different effect, such as causing constipation or difficulty
> in breathing.
>
> "If there is more than one receptor for a drug, which of the
> drug's actions are mediated by receptor A and which by
> receptor B?" asked Dr. Pasternak. "By identifying these
> receptors and learning how to control them, we could turn on
> only those that do what we want them to do."
>
> Dr. Pasternak's laboratory has taken a significant step in
> that direction by identifying specific mu receptors that
> govern morphine's pain-relieving effects using selective
> drugs synthesized in his laboratory. In more recent work with
> Dr. John E. Pintar of New Jersey's Robert Wood Johnson
> Medical School, the scientists selectively modified the genes
> in mice that create different mu receptors. Their research
> suggests that the mu receptor responsible for morphine
> analgesia is different from the mu receptors involved in the
> pain-dulling effects of heroin and M6G, a more powerful
> relative of morphine. In laboratory studies, the MSK
> researchers also identified a drug that blunted the desire to
> self-administer heroin, a finding that may someday prove
> useful for treating heroin addiction.
>
> WHAT'S NEW AT MSKCC.org
> ------------------------
>
> *Clinical Trials On-line Chat*
> August 4, 1999 8:00 to 9:00 p.m.
> Mark your calendars. It's just two days away. Memorial
> Sloan-Kettering Cancer Center experts will be on-line in a
> live chat session about clinical trials and what these
> studies can mean for cancer patients. Register now and come
> join the discussion Wednesday night.
> http://www.mskcc.org/document/chat_portal3.htm
> <a href="http://www.mskcc.org/document/chat_portal3.htm">
> AOL Users Click Here</a>
>
> *New and Noteworthy*
> -Improved treatment for colorectal cancer that has spread to
> the liver.
> -Scientists map out 3-D structure of tumor-suppressor
> protein.
> -Bone marrow transplantation helps children who experience a
> relapse of leukemia.
> http://www.mskcc.org/document/CN990805.htm
> <a href="http://www.mskcc.org/document/CN990805.htm">
> AOL Users Click Here</a>
>
>
> *MSK Fine-tunes Treatment for Breast Cancer*
> At a recent conference of the American Society for Clinical
> Oncology, MSK researchers outlined recent advances in the
> treatment of breast cancer. This report summarizes a few of
> the newest findings.
> http://www.mskcc.org/document/cn990801.htm
> <a href="http://www.mskcc.org/document/cn990801.htm">
> AOL Users Click Here</a>
>
> In Case You Missed It...
> -------------------------
> These items were mentioned in the last issue of
> Lately@MSKCC, but we wanted to make sure our new subscribers
> didn't miss them.
>
> *New Cancer Treatment Guidelines*
> The National Comprehensive Cancer Network and the American
> Cancer Society have released new treatment guidelines for
> breast-cancer and prostate-cancer patients. These guidelines
> are presented in an easy-to-follow format.
> http://www.nccn.org/patient_guidelines/default.htm
> <a
> href="http://www.nccn.org/patient_guidelines/default.htm">
> AOL Users Click Here</a>
>
> *Breast Reconstruction: A Personal Choice*
> After a mastectomy, a woman who wishes to have breast
> reconstruction has a number of options. This new area in our
> Breast Cancer Overview explains the various reconstruction
> techniques, and includes detailed illustrations.
> http://www.mskcc.org/document/reconstruct/personal.htm
> <a
> href="http://www.mskcc.org/document/reconstruct/personal.htm">
> AOL Users Click Here</a>
>
> *Integrative Medicine Service*
> This new MSK program offers the best of complementary
> therapies, including massage therapy, spiritual healing, art
> and music therapy, acupuncture, hypnotherapy, meditation,
> guided imagery and visualization, yoga, t'ai chi, nutritional
> counseling, and more.
> http://www.mskcc.org/document/integra1.htm
> <a href="http://www.mskcc.org/document/integra1.htm">
> AOL Users Click Here</a>
>
> ----------------------------------------------------
>
> *Feedback*
> Give us a compliment, if you'd like, or some suggestions
> using our feedback form.
> http://www.mskcc.org/feedback.cfm?address=lately@mskcc.org
> <a
> href="http://www.mskcc.org/feedback.cfm?address=lately@mskcc.org">
> AOL Users Click Here</a>
>
> If you experience problems with the Web site, send a message
> to our Webmaster. Please include as much information as
> possible about the problem.
> mailto:webmaster@mskcc.org
> <a href="mailto:webmaster@mskcc.org">
> AOL Users Click Here</a>
>
>
>
> You can subscribe to Lately@MSKCC at
> http://www.mskcc.org/document/lately.htm
>
> You can remove yourself from our mailing list at any time by
> following the directions at
> http://www.mskcc.org/unsub.htm
> <a href="http://www.mskcc.org/unsub.htm">
> AOL Users Click Here</a>
>
> ----------------------------------------------------
>
> Note: The information in Lately@MSKCC and at
> http://www.mskcc.org is not intended as a substitute for
> medical professional help or advice but is to be used only as
> an aid in understanding current medical knowledge. A
> physician should always be consulted for any health problem
> or medical condition.
>
> ----------------------------------------------------
>
> Copyright (C) 1999, Memorial Sloan-Kettering Cancer Center
> For information about republishing information from
> Lately@MSKCC, the Memorial Sloan-Kettering Cancer Center Web
> site at http://www.mskcc.org, or other MSKCC publications,
> mailto:publicaffairs@mskcc.org.
>
------------------------------------------------------------------------
This is an automatically-generated notice. If you'd like to be removed
from the mailing list, please visit the Medicine-On-Line Discussion Forum
at <http://www.meds.com/con_faq.html>, or send an email message to:
majordomo@lists.meds.com
with the subject line blank and the body of the message containing the line:
unsubscribe mol-cancer your-email-address
where the phrase your-email-address is replaced with your actual email
address.
------------------------------------------------------------------------
