[MOL] Depression In Breast Cancer Patients Linked To Lack Of Estrogen [01640] Medicine On Line


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[MOL] Depression In Breast Cancer Patients Linked To Lack Of Estrogen






Depression In Breast Cancer Patients Linked To Lack Of Estrogen
    [06/29/99; Doctor's Guide]

WASHINGTON, DC -- June 29, 1999 -- Breast cancer patients may
face an increased risk of depression as a result of treatment
that disrupts their bodies' supplies of estrogen, according to
the results of a pilot study conducted at Massachusetts General
Hospital, Boston. 

"Dysphoria, insomnia and hot flashes were almost universal in
women whose breast cancer treatment induced estrogen deficiency,"
said Donna Greenberg, M.D., one of the authors of the study.
"The rather abrupt change in estrogen adds to other adverse side
effects of adjuvant chemotherapy and presents another difficulty
for these patients." 

The researchers, led by Laura Sheingold Duffy, M.D., selected
21 breast cancer patients likely to develop estrogen deficiency.
The scientists conducted interviews regularly for an average
of 18 months after beginning treatment with chemotherapy and/or
tamoxifen. Eight women (38 percent) developed major depression,
most in the first six months of treatment. 

.....

The results of the study appear in the July-August issue of Psychosomatics.

The full article can be found at:

http://www.pslgroup.com/dg/10d582.htm


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