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HBX DNA May Be Critical in HCV-Related Liver Cancer
(CW HENDERSON PUBLISHER www.newsfile.com) -- Hepatitis B virus X-region DNA may be involved in the development of hepatocellular carcinoma in hepatitis C virus-positive patients with cirrhosis.
The risk of hepatocellular carcinoma (HCC) in patients chronically infected by hepatitis C virus (HCV) is higher in Japan than in Western countries. The presence of hepatitis B virus X (HBX)-DNA i ... (viewing 400 of 1590 total characters)
VEGF Has Vital Role in Metastasis
(CW HENDERSON PUBLISHER www.newsfile.com) -- Vascular endothelial growth factor plays an important role in lymph node metastasis through induction of angiogenesis in nasopharyngeal carcinoma, researchers report.
Recent findings indicate that angiogenesis affects tumor growth and metastasis. Vascular endothelial growth factor (VEGF) is considered to be an important regulator of tumor angi ... (viewing 400 of 2103 total characters)
High IL-8 and VEGF Levels Found in More Aggressive Disease
(CW HENDERSON PUBLISHER www.newsfile.com) -- Higher levels of interleukin-8 and vascular endothelial growth factor were associated with clinically more aggressive disease in patients with head and neck squamous carcinoma.
Insight into the interaction of angiogenic factors such as interleukin-8 and vascular endothelial growth factor may be beneficial in the treatment of head and neck squam ... (viewing 400 of 2829 total characters)
Troponin Suppresses Experimental Tumor Metastases
(CW HENDERSON PUBLISHER www.newsfile.com) -- Twice-weekly, relatively-low dosages of troponin I significantly suppressed experimental lung metastases in a rigorous animal model of metastatic melanoma.
Marsha A. Moses, The Children's Hospital, Boston, Massachusetts, and colleagues have purified a protein from cartilage that is a potent antiangiogenic molecule and have identified it as bein ... (viewing 400 of 2708 total characters)
Tumor Angiogenesis Evaluated As Prognostic Factor
(CW HENDERSON PUBLISHER www.newsfile.com) -- Although tumor angiogenesis is a prognostic factor for metastasis, researchers were unable to show significant correlation of angiogenesis with survival in patients with esophageal cancer.
T. Patel, Hematology Oncology Consultants, Inc., Columbus, Ohio, and colleagues in collaboration with researchers from the University of Cincinnati performed ... (viewing 400 of 2312 total characters)
VEGF Has Vital Role in Metastasis
(CW HENDERSON PUBLISHER www.newsfile.com) -- Vascular endothelial growth factor plays an important role in lymph node metastasis through induction of angiogenesis in nasopharyngeal carcinoma, researchers report.
Recent findings indicate that angiogenesis affects tumor growth and metastasis. Vascular endothelial growth factor (VEGF) is considered to be an important regulator of tumor angi ... (viewing 400 of 2103 total characters)
rK5 Inhibits Endothelial Cell Proliferation and Migration
(CW HENDERSON PUBLISHER www.newsfile.com) -- A kringle structure causes cell cycle arrest and apoptosis, researchers report.
Angiostatin which contains the first four kringle domains of plasminogen has been reported to be a potent inhibitor of angiogenesis. More recently, another kringle structure within plasminogen but outside angiostatin, known as kringle 5 (K5), was found to inhibit e ... (viewing 400 of 1438 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Social support and positive coping strategies improve the quality of life (QOL) of breast cancer patients under 50 years of age.
Nancy E. Avis, representing colleagues from the New England Research Institutes, Watertown, Massachusetts, presented data concerning the medical and psychosocial factors that affect QOL of newly diagnosed breast cance ... (viewing 400 of 3323 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Immunization with Mage3 or Melan-A peptide-pulsed autologous peripheral blood mononuclear cells (PBMC) plus recombinant human interleukin-12 (RhIL-12) makes an effective vaccination.
Thomas F. Gajewski, representing colleagues from the University of Chicago, Illinois, and the Genetics Institute, Massachusetts, presented data suggesting that eff ... (viewing 400 of 4816 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Tumor angiogenesis was less useful as a predictor of patient survival than was the stage of cancer in a group of patients with ovarian cancer.
Tumor angiogenesis has been shown to be important for tumor growth and the development of metastases. Increased intratumor microvessel density, an indicator of angiogenesis, has been shown to be a progn ... (viewing 400 of 2272 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Although tumor angiogenesis is a prognostic factor for metastasis, researchers were unable to show significant correlation of angiogenesis with survival in patients with esophageal cancer.
T. Patel, Hematology Oncology Consultants, Inc., Columbus, Ohio, and colleagues in collaboration with researchers from the University of Cincinnati performed ... (viewing 400 of 2312 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Tumor angiogenesis was less useful as a predictor of patient survival than was the stage of cancer in a group of patients with ovarian cancer.
Tumor angiogenesis has been shown to be important for tumor growth and the development of metastases. Increased intratumor microvessel density, an indicator of angiogenesis, has been shown to be a progn ... (viewing 400 of 2272 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Most medical students and physicians are unaware of the National Marrow Donor Program (NMDP), researchers reported recently.
This is despite the fact that more than 6,000 unrelated bone marrow transplant procedures
(CW HENDERSON PUBLISHER www.newsfile.com) -- Outpatient autologous stem cell transplantation (ASCT) is impractical for more than half of all transplant recipients, because it places caretaking responsibility on the patients' family and friends, researchers report.
The cost of high-dose therapy with ASCT for the treatment of malignant disease has decreased over recent years, and the number ... (viewing 400 of 3480 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Suicide gene therapy followed by concomitant chemotherapy after debulking surgery for recurrent ovarian cancer was well tolerated and non-toxic to patients.
A. Hasenburg, representing colleagues from the Freiburg University Medical Center, Germany, and the Baylor College of Medicine, Texas, presented data from a Phase I study of adenovirus-medi ... (viewing 400 of 3572 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- E2F-1 adenovirus (Ad)-mediated gene therapy is a promising strategy for MDM2-overexpressing cancers.
Kelly McMasters, representing colleagues from the University of Louisville, Kentucky, and the University of Texas M.D. Anderson Cancer Center, Texas, presented in vitro data showing the efficient killing of MDM2-overexpressing osteosarcoma cells ... (viewing 400 of 3309 total characters)
| CONFERENCE COVERAGE (ASCO) ... Radioimmunotherapy Socks Non-Hodgkin's Lymphoma |
CONFERENCE COVERAGE (ASCO) ... Angiogenesis Index As Prognostic Tool in Colorectal Cancer
(CW HENDERSON PUBLISHER www.newsfile.com) -- Angiogenesis was an independent prognostic variable in terms of local relapse-free survival in colorectal cancer patients, study findings show.
Several studies have indicated that the degree of tumor vascularization is an important prognostic parameter in human malignancies.
Alexandra Giatromanolaki and colleagues, Hellenic Cooperative ... (viewing 400 of 2546 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Elevated fibroblast growth factor levels may correlate with advanced disease stage in patients with multiple myeloma.
Fibroblast growth factor (FGF) is a well characterized stimulator for angiogenesis. Multiple myeloma (MM) bone marrow has increased microvessel density, recent findings show. Thalidomide, a molecule known to have anti-angiogen ... (viewing 400 of 2280 total characters)
(CW HENDERSON PUBLISHER www.newsfile.com) -- Bone mineral density (BMD) levels are reduced in men undergoing intermittent androgen suppression (IAS) for prostate cancer.
Celestia S. Higano, representing colleagues from the University of Washington at Seattle, presented data regarding the effects of IAS in prostate cancer patients without bone metastases at the 35th Annual Meeting of the A ... (viewing 400 of 4017 total characters)
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