All,
Just got off the phone with Julie Fiers (cancer connect nurse) at the
University of Wisconsin (Endostatin site). Here is some info about the
upcomming Endostatin trials there:
Principal Investigator: Dr. George Wilding
The clinical protocol has not yet been written for Endostatin. The
University has to write this, send it to the NCI, then the NCI sends it
back. This has something to do with the 6 months waiting period we keep
hearing about.
Entremed is still doing some stability testing on Endostatin before they
are ready to release it.
Some Eligibility requirments:
*No brain metastasis
*Patient must be able to be 'up and around' and take care of themselves
(example: light housework, etc)
*Patient has to have 'ordinary' lab tests results (example: kidney &
bone marrow ordinary with some fluctuation allowed)
*Patients will do multiple scans (pet, ct, mri, etc) to monitor response
to drug.
*Extensive time commitment for patients in trial required.
*Repeated biopsy's of tumor sites required.
Note: When I asked Julie if someone could possible get in under
compassionate use/single use investigational new drug, she said she
doubted that would be possilbe at phase 1 trial point.
God Bless
marty auslander
P.S. I keep hearing a small and fast phase 1 trial, with a much larger
phase two trial to follow. It is no longer a dream, folks,
Endostatin is ramping up and preparing.
It is going to happen! And soon! Hope is alive!
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