[MOL] More Information about Hycamtin and lung cancer/leukemia [12770] Medicine On Line


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[MOL] More Information about Hycamtin and lung cancer/leukemia



Hi once again. I am receiving much information about this therapy. HOpe
it doesn't overwhelm you, but I find it significant information to those
that are seeking a clearer understanding about the most positive effects
for therapy in their disease. More studies are coming to the front as a
result of some of the ongoing clinical trials. HOpe this information
benefits. Have a great day and God Bless

marty auslander


Hycamtin Activity Also Seen in Other Malignancies, Including Lung Cancer
and Leukemia

Recent studies have demonstrated that Hycamtin is active in other
malignancies including lung cancer, myelodysplastic syndrome (MDS) and
chronic myelomonocytic leukemia (CMML).  Last year, SmithKline Beecham
filed
a supplemental new drug indication for the use of Hycamtin in the
second-line
treatment of small cell lung cancer.  Hycamtin has been studied in over
200
clinical trials and is also being investigated for a number of other
cancers
including breast, colorectal and pediatric cancer, acute and chronic
leukemia,
as well as first-line combination chemotherapy in patients with ovarian
cancer.

Hycamtin, which is available for use in the United States in the
treatment of
recurrent, metastatic ovarian cancer, is also cleared for second-line
treatment of ovarian cancer in 15 European Union (EU) member countries
and is
under review with regulatory authorities in other major markets around
the
world.  This class of drugs kills cancer cells by inhibiting the enzyme
topoisomerase I, an enzyme which is essential in the replication of DNA
in
human cells.

SmithKline Beecham -- one of the world's leading healthcare companies --
discovers, develops, manufactures and markets pharmaceuticals, vaccines,
over-the-counter medicines and health-related consumer products, and
provides
healthcare services including clinical laboratory testing, disease
management
and pharmaceutical benefit management.  For company information, visit
SmithKline Beecham on the World Wide Web at http://www.sb.com.

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