Dear Bob,
Strongly suggest they communicate with NCI at http://www.nci.nih.gov
They will be able to access the clinical unit of the National Cancer
Institute in Bethesda, Md who would be in the best position to respond to
this.
John
Robert W. Neill, Jr. wrote:
>
> Request For Assistance - Soviet Georgia
>
> This is reposted from CANCER@RWNEILL.COM
> http://rwneill.com
>
> Organization: Children hospital N3
> Reply-To: maia@children.kheta.ge
> From: maia@children.kheta.ge (Maia Kherkheulidze)
> Date: Fri, 24 Apr 1998 11:36:22 +0400 (MSD)
> X-Mailer: dMail [Demos Mail for Windows v1.2 Professional]
> Subject: Patient
> Lines: 88
>
> Patient - Mdzinarishvili Zurab
> Age - 4 years and 10 months
> Sex - male
> Lives in Tbilisi, Georgia
>
> Disease began in December 1997 with cough, general weakness,
> fever, respiratory disorders. Initially was diagnosed and treated as
> pneumonia.
> Several studies were performed and lymposarcoma was suspected.
>
> The first CT study, performed on 16.02.98 revealed on I-II lumbar vertebras
> level on small intestine
> mesentery projection lymphatic nodes of 0,3-0,5 cm size. On the same level
> in front of the inferior
> vena cava was seen a tissular area with distinct, rough, polycycle surface,
> of 2 cm size, which was
> considered a conglomerate of limphatic nodes.
>
> The second CT study was conducted on 21.03.98. It revealed on I-II lumbar
> vertebras level a tissular
> structure with round, rough form and distinct outlines. It occupies
> projection field of rostral offshot pancreas
> (The Structure was considered a conglomerate of lymphatic nodes).
> The lymphatic nodes of 0,6 cm size were seen on projection of small
> intestine mesentery
> (Positive dynamics comparing to the previous study).
>
> General blood Test:
>
> Date: 12.02 19.02 23.02
> 02.03 06.03 16.03 20.03 27.03
>
> Hemoglobin g\l 100 126 116
> 120 120 133 126 130
> Erythrocyte 3,6 4,0 3,7
> 4,1 4,3 4,3 4,1
> 4,5
> Color factor - 0,94 0,95
> 0,88 0,84 0,93 0,93
> 0,87
> Thrombocytes per 1000 - 40 60
> 60 50 50 50 50
> Leukocytes 24,0 11,6 11,8
> 6,5 7,2 7,7 10,0 13,7
> Mielocytes % - 0,5 -
> - - -
> - -
> Metamyelocytes % - - -
> - - - -
> -
> Neutrophils-"bends"% 2 3,5 -
> - - - 1
> -
> Neutrophils-"segs" % 14 13 12
> 30 31 30 24 23
> Eosinophils % 71 48 45
> 25 28 27 30
> 30
> Basophils % - - -
> - - -
> - -
> Lymphocytes % 10 30,5 32
> 26 37 37 35
> 41
> Monocytes % 3 4,5 11
> 5 4 5 9
> 5
> ESR 38 32 31
> 26 21 20 18
> 8
>
> Results of the serological study on yersinial infection and tuberculosis
> was negative.
>
> Biochemical blood test:
> AST - 17 units \ liter, ALT - 18 units \ liter, Sialus acid -
> 150, "O"-strephtolisine - 125,
> "C"-reactive protein - (---), rhevmatoid factor - (---)
>
> Study medulla marrow:
>
> Mieloblastus - 0,25%
> Promielocytes - 0,25%
> Mielocytes - 5,25%
> Metamielocytes - 3,25%
> Lymphocytes - 20,75%
> Monocytes - 0,5%
> Plasma cells - 0,25%
>
> Neutrophils-"bends" - 5,0%
> Neutrophils-"segs" - 15,25%
>
> Eosinophils:
> Promielocytes - 0,25%
> Mielocytes - 5,25%
> Metamielocytes -1,25%
> Neutrophils-"bends" - 2,25%
> Neutrophils-"segs" - 34,0%
>
> General urine test and urine test on bilirubin without changing.
> Apart from this in the research institute of Parasitology laboratory
> studies on helminthosis were conducted.
> Negative answers were received on all events.Specialist from the research
> institute of Parasitology
> suspected Fascioliasis, unfortunately they an were unable to conduct
> specific study.
> >From their point of view the disease is in the incubation stage which
> will finish at the end of April.
> At present the patient's condition is unsatisfactory. Respiratory disorders
> still occur (cough, weakness).
> High eosinophilys, changes on CT are unexplained.
>
> We would request:
> Your opinion on the diagnosis
>
> Looking forward for your reply.
> Thank you in advance.
> Sincerely yours,
>
> Ivane Chkhaidze MD
> Deputy director
> Michael Guramishvili Pediatric Clinic
> Tbilisi, Georgia
>
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