Dear Cindy,
My understanding thus far is.....it will cure all cancers. That is what
the article says and that is what some of the researchers have said as
well. Although of course there are the cautions of false hope about
working in mice as opposed to humans. I believe a website posted by
Gyles Friedman may explain more. Here they are again. HOpe this is a
little more encouraging but the news is vague in a sense, but more
hopeful than all the other treatments that we have been accustomed to
when first going into clinical trials. AGain, this information was in
the article. Thank you for your request.
God Bless
marty auslander
>From what we know, clinical trial with angio and endostatins will be
available
in about one year. There are other promising NCI sponsored clinical
trials for
stage IV pancreatic cancer due to start shortly. I am not home where the
precise information is, but I'll send you some better description with a
phone
number to call tomorrow morning.
* Gilles Frydman gfrydman@acor.org
* The Association of Cancer Online Resources, Inc.
* http://www.acor.orghttp://www.medinfo.org
Cindy Crowe wrote:
>
> Marty,
>
> I may be asking questions before enough knowledge has been made public but
> here goes:
>
> 1) Since the press release mentioned tumors does that leave out
> leukemia or, as in Jim's case, where his cancer has spread into his bone
> marrow?
>
> Like I say, I know this may be asking too many questions before more info is
> released but it sounds just wonderful and I'm curious about how it affects
> blood cancer or even if that has been researched yet.
>
> Thanks for the information. If this works as well in humans as in mice, we
> will all be priveledged to see the world change as this could mean cures for
> almost all types of cancer. Right??
>
> Thanks so much for sharing.
>
> Luv you & Barb,
>
> cindy
>
> -----Original Message-----
> From: Martin Auslander <fitecancer@earthlink.net>
> To: Medical On Line Forum <mol-cancer@lists.meds.com>
> Cc: BabooA@earthlink.net <BabooA@earthlink.net>
> Date: Monday, May 04, 1998 2:55 AM
> Subject: [MOL] A Possible Cancer Cure - Endostatin/Angiostatin
>
> >My Dear Friends. It has been, needless to say very strained weekend for
> >
> >many, but if I may say this: When one door closes another opens, and I
> >
> >am encouraged to have learned about the following. I have been in
> >
> >contact with the N.C.I. and they are and will be providing information
> >
> >on clinical trials in the near future. So, with this very good news I am
> >
> >hoping we can come together, with a sigh of some relief, in unity to
> >
> >shout with glee that finally what we have been strained and in stress
> >
> >about, may be coming to a conclusion of great hope and cure. Pls join me
> >
> >in praying for that. I am certain you will find the following article to
> >
> >be the best HOPE we have had to date about cure, God Willing.
> >
> >
> >
> >God Bless
> >
> >marty auslander
> >
> >
> >
> >
> >
> >2 DRUGS MAY BE CANCERS NEMESIS:
> >
> >
> >
> >HEALTH: Angiostatin and endostatin are shown to halt the disease in
> >
> >mice. HOpe is high for human tests.
> >
> >
> >
> > Within a year, if all goes well, the first cancer patient will be
> >
> >injected with two new drugs that can eradicate any, ANY, type of cancer,
> >
> >with no obvious side effects, and no drug resistance - in mice.
> >
> > Some cancer researchers say the drugs are the most exciting treatment
> >
> >that they have ever seen. But the expectations are tempered with caution
> >
> >as that the history of cancer expectations of high hopes, are dashed
> >
> >with remarkable effects in animals and then tested in people.
> >
> > National Cancer Institute has made the drugs their top priority said
> >
> >Dr. Klausner, the Director. I am putting nothing on higher priority than
> >
> >getting this into clinical trials".
> >
> > The new drugs, angiostatin and endostatin, work by interfering with the
> >
> >blood supply tumors need. Given together, they make tumors disappear and
> >
> >not return.
> >
> > So far, the drugs are the only ones ever tested that can seemingly
> >
> >eradicate all tumors in mice, even gigantic ones, equivalent to 2 pound
> >
> >growth in a person. The best that other cancer drugs have done is slow
> >
> >the growth.
> >
> > The drug discoverer, Dr. Judah Folkman, a cancer researcher at
> >
> >Childrens Hospital in Boston, is cautious about drugs promise. Until
> >
> >patients take them, he said, it is dangerous to make predictions.
> >
> > Other researchers are not so restrained. "Judah is going to cure cancer
> >
> >in two years", said Dr. James Watson, a Nobel laureate.
> >
> > Results of mice tests follows (Not for the weak hearted).
> >
> >
> >
> >After 15 days, the researchers killed the mice and cut them open. As
> >
> >more than a dozen scientists gathered around a table in the laboratory,
> >
> >the first mouse was opened. It had huge tumors filling its lungs. Then
> >
> >Dr. Folkman checked a noteboook to see what the animal had received:
> >
> >salt water. They looked at the next mouse. NO tumors. Folkman checked to
> >
> >see the treatment: angiostatin. And so it went. All 10 of the mice that
> >
> >had b een injected with angiostatin were free of cancer. All 10 of those
> >
> >that had been received salt water had huge new tumors.
> >
> > A picture of the mouse in the article clearly indicates that the cancer
> >
> >shrunk to almost nothing, but sometimes returned when treatment stopped
> >
> >with either endostatin or angiostatin. AFter several weeks of
> >
> >injections with both drugs, the cancer shrinks to nothing and does not
> >
> >return.
> >
> >
> >
> >Orange county Register dated may 3, 1998.
> >--
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