Re: [MOL] response to your inquiry re: Rituxin [02735] Medicine On Line


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Re: [MOL] response to your inquiry re: Rituxin




Hi,
I read your mail on Rituxin. My mother is suffering from Intestinal 
cancer and was operated in August 1997. She was then put on chemotherapy 
for 6 cycles.5 FU was administered for the first 4 cycles and 5FU and 
Mytomycin was given for the fourth cycle. However the disease spread to 
the liver as the scans showed after the 4th cycle. She was administeredd 
CISPLATIN for the last 2 cycles. However the disease still seems to be 
increasing. Will Rituxin work for my mother?  OR Do you have any other 
drug that will help? Please help me as the doctor's project a very grim 
outlook here.
Please write to me at 
ghantu@hotmail.com

Best regards
Sam 
>
>I am a registered nurse, but more importantly, I have NHL.  I was 
diagnosed
>September 1996, treated with radiation only, and since then have read
>everything I can get my hands on re:  lymphoma...  I am a member of the
>Lymphoma Research Foundation which offers the most up-to-date info on 
clinical
>trials etc.  The Sept. and Dec. newsletters addressed Rituxin. It was 
just
>approved by the FDA .  I live in the Tidewater area of Virginia 
(actually, VA.
>Beach) and my oncologist is administering Rituxin.  He has given about 
12
>patients the treatment and it is too soon to tell the results.  (It was 
only
>approved late November.)  He does feel optomistic though.
>
>A close friend of mine completed the 'Chop' chemo treatment 3 mos. ago 
(she
>was stage 4) and a follow-up bone marrow biopsy determined the lymphoma 
was
>still in her bone marrow.  Last Friday, she had her first Rituxin 
treatment.
>It can take up to 12 hours to administer due to patients having 
allergic
>responses (fever, drop in blood pressure etc.).  If this occurs, the 
drip is
>slowed or stopped for a spell, and then restarted.  My friend's 
treatment was
>completed in 4.5 hours and she felt great (still does!)  She was given
>Decadron, Benadryl and Tylenol prior to treatment administration to 
curb the
>allergic responses and she did great.  The protocol for treatment is 4
>treatments, each a week apart.  The first one will last the longest.  
They
>anticipate that my friend's next treatment will be about 3 hours.
>
>The most exciting aspect of Rituxin is that it can be given repeatedly 
and it
>does not deplete one's immune system the way chemo and radiation do.  
It is my
>firm belief that this depletion and subsequent set-up for infection is 
what
>gets us, not the Lymphoma.
>
>Good luck to your sister-in-law and I'd love to know more about her!  
We all
>need to stick together!
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