Very informative Marty. Thanks for posting it.
Christine
At 07:07 AM 01/10/98 -0700, you wrote:
>Good Morning My Friends,
>
>Am passing on this info, and someone may have posted here already, but
>since I have been absent from this list for two weeks am unable to
>determine what has been posted or not. If this message has been postage,
>then ignore me.....as my wife does, LOl.
>
>God Bless
>marty auslander
>
>Calcium-D-Glucarate:
>The Newest Breast Cancer Prevention
>from "Let's Live" magazine, August 1998
>by Sherry A. Rogers M.D.
>
> The medical community has known for many years that prescribed
>estrogens, used in oral contraceptives and postmenopausal and post-
>hysterectomy estrogen replacement therapies, increase the risk of
>breast cancer. This led women who opted not to use oral contraceptives
>or estrogen replacement to think that they could rule estrogen off
>their own risk lists for this often deadly disease. Now, however,
>evidence is surfacing that suggests that these estrogen mimics pose a
>risk for all of us.
> Scientists studying a high rate of breast cancer in Long Island
>found that women with breast cancer had higher levels of pesticides
>such as DDT in their breasts than women with normal breasts. What is
>the link between pesticides and estrogen? It turns out that many
>pesticides mimic the action of estrogen once they get into the body,
>including triggering cancer. DDT is one of these chemicals. Atrazine,
>the most common herbicide used on corn, is another.
> But the plot thickens. The plastic wrap you use on your vegetables,
>fruits and meats also contains these estrogen mimics. And the plastic
>bottles that hold your soda, spring water and even baby's formula all
>contain this same class of chemicals. They leach into food and drinks
>and are most likely contributing to the epidemic increase in breast
>cancer.
> Scientists around the world are astounded at how many estrogen
>mimics the average person is exposed to. Even though these everyday
>chemicals don't resemble the estrogen molecule in chemical structure,
>they nevertheless cause potent estrogenic activity once in the body.
>Proof is mounting that these widespread environmental chemicals called
>xenobiotics or xenoestrogens are partially responsible not only for
>cancers, but also for the escalating rate of infertility and other
>unusual animal and human symptoms.
> Environmental estrogen mimics were accidentally discovered in a
>research laboratory because the xenoestrogens in plastic test tubes
>were interfering with other chemicals being studied. One of the most
>common environmental estrogens is a group called alkylphenolic
>compounds.
>Once these compounds are in the body, they wreak havoc in several ways.
>First, they bond with estrogen receptors like a woman's
>estrogen-estradiol.
>After attaching to a receptor, they transmit a messsage that tells
>breast
>cancer cells to grow. Second, estrogens signal the release of a chemical
>known as "tumor growth factor." And third, xenoestrogen can even cause
>the number of receptor cells to proliferate. Once activated, they
>stimulate breast cancer cell growth; hence, they contribute to several
>of cancer's mechanisms.
> Scientists have estimated that 50 to 95 percent of cancers are
>caused by diet and environment; xenoestrogens are present in both for
>most women. They are very common in paints, textiles, paper products,
>pesticides, herbicides, plastics and plastic wraps. Some of the highest
>levels come from detergents that are used heavily in commercial
>enterprises and end up in municipal water supplies. And, they also
>migrate into foods from packaging.
> The best news is that you can rev up or supercharge your body's
>estrogen detoxification pathway to get rid of these xenoestrogens more
>efficiently. You have control over the amount of estrogenic compounds
>that the body detoxifies and eliminates, rather than storing. Here's
>how:
> In order to detoxify an estrogen-like compound, the liver hooks a
>heavy molecule into it called a glucuronide. This estrogen-glucuronide
>complex is carried out of the liver into the bile and down the gut. But
>intestinal bacteria make an enzyme that rips the glucoronide conjugate
>off the estrogen. Then, the estrogen is free to be absorbed back into
>the body to do its damage.
> This nasty reabsorption is called "entero-hepatic circulation,"
>meaning the estrogen-mimic comes out of the gut and into the liver
>again, from which it can return to the bloodstream. The result is that
>the body has wasted energy and nutients in detoxifying it, only to have
>it return. Hence, you are worse off than when you started, because
>you've lost nutrients in the process.
> Luckily, there are at least three ways to control how much
>estrogen is reabsorbed into your bloodstream. One way is to eat a
>no-meat diet, because eating meat raises the level of glucuronidase
>in the gut.
> Second, since the phytochemical indole-3-carbinol also revs up the
>glucuronidation pathway, you can eat at least two vegetables from the
>indole-rich cruciferous family, such as broccoli, cauliflower, cabbage,
>Brussels sprouts, kale and collards, every day.
> The third option is to take Calcium-D-glucarate, which prevents
>the bacterial enzyme glucuronidase from ripping the glucuronide off.
>Calcium-D-glucarate helps the estrogen-glucuronide complex to keep
>moving through the bowel and out of the body.
> Calcium-D-glucarate is so potent that when it was given to rats
>specially bred to have a 100-percent risk of breast cancer, only 56
>percent got it. And the animals that did get it had 87.5 percent fewer
>tumors than normal. In fact, Calcium-D-glucarate is so promising as an
>adjunct cancer therapy that the National Institutes of Health is
>studying its use by women.
> Unfortunately, the environment is loaded with estrogen mimics that
>can be carcinogenic in adults, as well as children. The good news is
>that Calcium-D-glucarate can cut the risk. And by taking other steps
>to reduce your total load - cutting down on exposure sources, eating
>six to nine servings of fresh fruits and vegetables a day, eating less
>meat, plus taking antioxidants - you'll have an increased chance of
>preventing not only breast cancer, but other forms of chemically-
>induced cancers.
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