LINHILLIS@aol.com wrote:
>
> Hi everyone
>
> Thought you might find this article interesting. Something to keep an ear
> open for in the near future.
> Hope everyone has a good weekend. My husband & I are going to NYC
> to see our daughter for a few days. Will talk with you next week.
> Take care
> Diana
> ---------------------
> Forwarded message:
> From: mrudner@CCS.CARLETON.CA (Martin Rudner)
> Sender: LUNG-ONC@LISTSERV.ACOR.ORG (LUNG-ONC: The Lung Cancer Online Support
> Group)
> Reply-to: LUNG-ONC@LISTSERV.ACOR.ORG (LUNG-ONC: The Lung Cancer Online
> Support Group)
> To: LUNG-ONC@LISTSERV.ACOR.ORG
> Date: 97-10-30 08:30:36 EST
>
> I thought this news item would be of interest to members of this group.
> While the first phase testing will (apparently) be on colon cancer, this
> approach is said to be also relevant to other adenocarcinimas, including
> lung and ovarian cancers:
>
> Reuters New Media
>
> > Thursday October 30 6:43 AM EST
> >
> > Doctors Take Aim at Cancer With Magic Bullet
> >
> > LONDON (Reuters) - Scientists are close to testing a genetically
> > engineered "magic bullet" that could treat half of the most common
> > cancers, New Scientist magazine said Wednesday.
> >
> > Early laboratory tests have shown that the "bullets," which destroy
> > the tumors by injecting them with a deadly toxin, were effective in
> > treating adenocarcinomas which are found in lung, ovary, prostate,
> > colon and breast cancers.
> >
> > Clinical trials with colon cancer sufferers could begin within the
> > next 15 months.
> >
> > A magic bullet is a treatment that targets the cancerous cells without
> > harming any of the healthy cells around them -- unlike chemotherapy
> > which can harm healthy cells and result in serious side-effects.
> >
> > "Medical Targeting Recognition (MTR) Technologies, the Jerusalem-based
> > company that developed the bullets, say that they might work better
> > than other such treatments because their toxins actually penetrate
> > cancer cells," the magazine said.
> >
> > Earlier attempts at the approach failed because although the
> > antibodies on the bullets found the cancerous cells they could not
> > penetrate and destroy them without harming healthy cells as well.
> >
> > MTR developed fusion proteins that isolate the dangerous cells and
> > inject them with a bacterial toxin while leaving healthy cells alone.
> >
> > One half of the re-engineered protein binds to the receptor on
> > adenocarcinoma cells and the second half fires a fatal dose of the
> > toxin that kills them by preventing them from making proteins.
> >
> > "The Israelis modified the natural toxin so that immune cells
> > previously exposed to the bacteria would not recognize and attack it,"
> > the magazine explained.
> >
> > Seragen, a Massachusetts-based company, is using a similar approach
> > against a rare form of leukemia called cutaneous T cell lymphoma.
> >
> > Its protein binds to a site on the cancer cells called interleukin-2
> > growth factor receptor to fire the toxin. It is already close to
> > completing clinical trails and is applying to the U.S. Food and Drug
> > Administration for approval of the drug. ^REUTERS@
> > _________________________________________________________________
> >
> > Earlier Related Stories
> > * Doctors Take Aim at Cancer With Magic Bullet - Wed Oct 29 11:28 pm
> > _________________________________________________________________
> >
> > ________________________ Search News Help
> > _________________________________________________________________
> >
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> > _________________________________________________________________
> >
> > [ Index | News | World | Biz | Tech | Politic | Sport | Scoreboard |
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> > _________________________________________________________________
> >
> > Reuters Limited
> >
> >
> > Questions or Comments
> >
>
> ----------------------------------------------------------------------
> Professor Martin Rudner, Ph.D.,
> The Norman Paterson School of International Affairs,
> Carleton University,
> Ottawa, Ontario K1S 5B6
> Canada
>
> Phone: (613) 520-2600 X6659 FAX (613) 520-2889
> Email address: mrudner@ccs.carleton.ca
> ----------------------------------------------------------------------
>
> Dearest Diana,
Have a great weekend with your family. We will miss you and thx for the
information. I have passed this message onto an ovarian discussion
listserv as well. Take care and talk with you next week.
God Bless You
Marty Auslander
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