DISEASE: Testicular

Select a REGIMEN:

BEP
PVB
VIP #1
VIP #2

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DISEASE: Testicular

REGIMEN: BEP

ETOPOSIDE [VP-16] 100 mg/m2 per day IV...D1-5
(reduce by 20% if prior XRT)

CISPLATIN [CDDP] 20 mg/m2 per day IV...D1-5

BLEOMYCIN [BLEO] 30 units IV...D2,9,16
Caution: Monitor cumulative dose (pulmonary toxicity)

CYCLE: 21 days
REFER: Williams SD, et al: NEJM 1987; 316:1435-1440.

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DISEASE: Testicular

REGIMEN: PVB

CISPLATIN [CDDP] 20 mg/m2 per day IV...D1-5

VINBLASTINE [VLB] .15 mg/kg IV...D1,2
(reduce 20% if prior XRT)

BLEOMYCIN [BLEO] 30 units IV...D2,9,16
Caution: Monitor cumulative dose (pulmonary toxicity)

CYCLE: 21 days x 4 courses
REFER: Williams SD, et al: NEJM 1987; 316:1435-1440.

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DISEASE: Testicular

REGIMEN: VIP #1

ETOPOSIDE [VP-16] 75 mg/m2 per day IV...D1-5

IFOSFAMIDE [IFF] 1.2 g/m2 per day x 5 CIV...D1-5

CISPLATIN [CDDP] 20 mg/m2 per day IV...D1-5

MESNA [MESNA] 400 mg/m2 IV...D1
15 min. pre ifos

MESNA [MESNA] 1.2 g/m2 per day x 5 CIV...D1-5
start immediately after bolus MESNA

CYCLE: 21 days
REFER: Loehrer PJ, et al: ANN INTERN MED 1988; 109:540-546.

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DISEASE: Testicular

REGIMEN: VIP #2

VINBLASTINE [VLB] .11 mg/kg per day IV...D1,2

IFOSFAMIDE [IFF] 1.2 g/m2 per day x 5 CIV...D1-5

CISPLATIN [CDDP] 20 mg/m2 per day IV...D1-5

MESNA [MESNA] 400 mg/m2 IV...D1
15 min. pre ifos

MESNA [MESNA] 1.2 g/m2 per day x 5 CIV...D1-5
start immediately after bolus MESNA

CYCLE: 21 days
REFER: Loehrer PJ, et al: ANN INTERN MED 1988; 109:540-546.

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