Lung: Small Cell Regimens

DISEASE: Lung: Small Cell

Select a REGIMEN:

DISEASE: Lung: Small Cell

REGIMEN: CAE

CYCLOPHOSPHAMIDE

DOXORUBICIN [DOX] 45 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)

ETOPOSIDE [VP-16] 50 mg/m2 per day IV...D1-5

CYCLE: 3 weeks
REFER: Rudolph A, et al: PROC ASCO 1983; 2:192.

DISEASE: Lung: Small Cell

REGIMEN: CAV

CYCLOPHOSPHAMIDE

DOXORUBICIN [DOX] 40 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)

VINCRISTINE [VCR] 1 mg/m2 IV...D1
Maximum dose is 2 mg

CYCLE: 21 days for 6 cycles
REFER: Roth BJ, et al: J CLIN ONCOL 1992; 10:282-291.

DISEASE: Lung: Small Cell

REGIMEN: CAVE

CYCLOPHOSPHAMIDE

DOXORUBICIN [DOX] 50 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)

VINCRISTINE [VCR] 1.5 mg/m2 IV...D1
Maximum dose is 2 mg

ETOPOSIDE [VP-16] 60 mg/m2 per day IV...D1-5

CYCLE: 3-4 wks
REFER: DeVore RF, et al: Current Therapy in Hematology-Oncology. Brain MC, Carbone PP,eds. 4th Ed. B.C.Decker 1992;274-278.

DISEASE: Lung: Small Cell

REGIMEN: CEV

CYCLOPHOSPHAMIDE

ETOPOSIDE [VP-16] 50 mg/m2 IV...D1

ETOPOSIDE [VP-16] 100 mg/m2 per day PO...D2-5

VINCRISTINE [VCR] 1.4 mg/m2 IV...D1
max dose 2mg

CYCLE: 21 days
REFER: Comis RL: SEMIN IN ONCOL 1986; 13(Suppl 3):40-44.

DISEASE: Lung: Small Cell

REGIMEN: EP

CISPLATIN

ETOPOSIDE [VP-16] 100 mg/m2 per day IV...D1-3

CYCLE: 3 weeks
REFER: DeVore RF, et al: Current Therapy in Hematology-Oncology. Brain MC, Carbone PP,eds. 4th Ed. B.C.Decker 1992;274-278.

DISEASE: Lung: Small Cell

REGIMEN: VIP(ICE)-1

IFOSFAMIDE

CISPLATIN [CDDP] 20 mg/m2 per day IV...D1-4

ETOPOSIDE [VP-16] 37.5 mg/m2 per day PO...D1-21

CYCLE: 28 days
REFER: Faylona E, et al: PROC ASCO 1992; 11:307.

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