Lung: Sarcoma: Soft Tissue Regimens

DISEASE: Sarcoma: Soft Tissue

Select a REGIMEN:

DISEASE: Sarcoma: Soft Tissue

REGIMEN: A-DIC

DOXORUBICIN

DACARBAZINE [DTIC] 200 - 250 mg/m2 per day IV over 1h... D1-5

CYCLE: 3 weeks
REFER: Baker LH, et al: J CLIN ONCOL 1987; 5:851-861.

DISEASE: Sarcoma: Soft Tissue

REGIMEN: CYADIC

CYCLOPHOSPHAMIDE

DOXORUBICIN [DOX] 40 - 60 mg/m2 IV... D1
Caution: Monitor cumulative dose (cardiac toxicity)

DACARBAZINE [DTIC] 200 - 250 mg/m2 per day IV... D1-5

CYCLE: 21 days
REFER: Baker LH, et al: J CLIN ONCOL 1987; 5:851-861.

DISEASE: Sarcoma: Soft Tissue

REGIMEN: CYVADIC

CYCLOPHOSPHAMIDE

VINCRISTINE [VCR] 1.5 mg/m2 IV... D1,5
max dose 2mg

DOXORUBICIN [DOX] 40 - 50 mg/m2 IV... D1
Caution: Monitor cumulative dose (cardiac toxicity)

DACARBAZINE [DTIC] 200 - 250 mg/m2 per day IV... D1-5

CYCLE: 21 days
REFER: Yap B-S, et al: CA TREAT REP 1980; 64:93-98.

DISEASE: Sarcoma: Soft Tissue

REGIMEN: MAID

MESNA

DOXORUBICIN [DOX] 20 mg/m2 per day x 3 CIV... D1-3
(Total Dose 60 mg/m2)
Caution: Monitor cumulative dose (cardiac toxicity)

IFOSFAMIDE [IFF] 2500 mg/m2 per day x 3 IV... D1-3

DACARBAZINE [DTIC] 300 mg/m2 per day x 3 CIV... D1-3
(Total Dose 900 mg/m2)

CYCLE: 21 days
REFER: Elias AD, et al: PROC ASCO 1987; 6:134.

DISEASE: Sarcoma: Soft Tissue

REGIMEN: VAC

VINCRISTINE

DACTINOMYCIN [DAC] .015 mg/kg per day IV... D1-5
q 3 months x 5 courses (max 0.5mg per day)

CYCLOPHOSPHAMIDE [CTX] 2.5 mg/kg per day PO... daily
for 2 years

CYCLE: None
REFER: Wilbur JR, et al: CANCER 1975; 36:765-769.

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