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DoseCalc OnLine
spacer Guide To Oncology Regimens

DISEASE: Ovarian

Select a REGIMEN:

AP
CC
CHAD/IV
CHAP
CP
HEXA-CAF
PAC-1
PACLITAXEL



DISEASE: Ovarian

REGIMEN: AP

    DOXORUBICIN [DOX] 50 mg/m2 IV...D1
    Caution: Monitor cumulative dose (cardiac toxicity)

    CISPLATIN [CDDP] 50 mg/m2 IV...D1

CYCLE: 21 days
REFER: Bruckner HW, et al: PROC ASCO 1979; 20:414.




DISEASE: Ovarian

REGIMEN: CC

    CARBOPLATIN [CBDCA] 300 - 350 mg/m2 IV

    CYCLOPHOSPHAMIDE [CTX] 600 mg/m2 IV

CYCLE: 28 days
REFER: Skeel RT: Handbook of Cancer Chemotherapy, 3rd Ed. Little, Brown & Co. 1991; 210.




DISEASE: Ovarian

REGIMEN: CHAD/IV

    CYCLOPHOSPHAMIDE [CTX] 400 mg/m2 I...D1

    ALTRETAMINE [HMM] 150 mg/m2 per day PO...D2-8

    DOXORUBICIN [DOX] 30 mg/m2 IV...D1
    Caution: Monitor cumulative dose (cardiac toxicity)

    CISPLATIN [CDDP] 60 mg/m2 IV...D1

CYCLE: 28 days
REFER: Edmonson JH, et al: CANCER TREAT REP 1985; 69:1243-1248.




DISEASE: Ovarian

REGIMEN: CHAP

    CYCLOPHOSPHAMIDE [CTX] 150 mg/m2 per day PO...D2-8

    ALTRETAMINE [HMM] 150 mg/m2 per day PO...D2-8

    DOXORUBICIN [DOX] 30 mg/m2 IV...D1
    Caution: Monitor cumulative dose (cardiac toxicity)

    CISPLATIN [CDDP] 50 mg/m2 IV...D1

CYCLE: 28 days
REFER: Bruckner HW, et al: PROC ASCO 1979; 20:414.




DISEASE: Ovarian

REGIMEN: CP

    CYCLOPHOSPHAMIDE [CTX] 1000 mg/m2 IV

    CISPLATIN [CDDP] 50 mg/m2 IV

CYCLE: 21 days
REFER: Decker DG, et al: OBSTET GYNECOL 1982; 60:481-487.




DISEASE: Ovarian

REGIMEN: HEXA-CAF

    ALTRETAMINE [HMM] 150 mg/m2 per day PO...D1-14

    CYCLOPHOSPHAMIDE [CTX] 150 mg/m2 per day PO...D1-14

    METHOTREXATE [MTX] 40 mg/m2 IV...D1,8

    FLUOROURACIL [5-FU] 600 mg/m2 IV...D1,8

CYCLE: 28 days
REFER: Young RC, et al: NEJM 1978; 299:1261-1266.




DISEASE: Ovarian

REGIMEN: PAC-1

    CISPLATIN [CDDP] 50 mg/m2 IV...D1

    DOXORUBICIN [DOX] 45 mg/m2 IV...D1
    Caution: Monitor cumulative dose (cardiac toxicity)

    CYCLOPHOSPHAMIDE [CTX] 600 mg/m2 IV...D1

CYCLE: 28 days
REFER: Conte PF, et al: J CLIN ONCOL 1986; 4:965-971.




DISEASE: Ovarian

REGIMEN: PACLITAXEL

    PACLITAXEL [TAX] 135 mg/m2 CI over 3 hrs...D1

CYCLE: 21 days
REFER: TAXOL(R) (paclitaxel) Bristol-Myers Squibb Co, prescribing info in PHYSICIANS DESK REFERENCE 49th Ed. Montvale,NJ; 1995;682.




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