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DISEASE: Head and Neck
Select a REGIMEN:
CF
COB
MBC
METHOTREXATE
PFL
DISEASE: Head and Neck
REGIMEN: CF
CYCLE: 21 days
REFER: Kish JA, et al: CANCER 1985; 56:2740-2744.
DISEASE: Head and Neck
REGIMEN: COB
CISPLATIN [CDDP] 100 mg/m2 IV...D1
VINCRISTINE [VCR] 1 mg IV...D2,5
Maximum dose is 2 mg
BLEOMYCIN [BLEO] 30 units per day x
4 CIV...D2-5
Caution: Monitor cumulative dose (pulmonary toxicity)
CYCLE: 21 days
REFER: Skeel RT: Handbook of Cancer Chemotherapy, 3rd Ed. Little,
Brown & Co. 1991; 152.
DISEASE: Head and Neck
REGIMEN: MBC
METHOTREXATE [MTX] 40 mg/m2 IM or
IV...D1,15
BLEOMYCIN [BLEO] 10 units IM or
IV...D1,8,15
Caution: Monitor cumulative dose (pulmonary toxicity)
CISPLATIN [CDDP] 50 mg/m2 IV...D4
CYCLE: 21 days
REFER: Skeel RT: Handbook of Cancer Chemotherapy, 3rd Ed.
Little, Brown & Co. 1991; 153.
DISEASE: Head and Neck
REGIMEN: METHOTREXATE
METHOTREXATE [MTX] 40 - 60 mg/m2
IV...weekly
CYCLE: None
REFER: Skeel RT: Handbook of Cancer Chemotherapy, 3rd Ed.
Little, Brown & Co. 1991; 145-146.
DISEASE: Head and Neck
REGIMEN: PFL
CISPLATIN [CDDP] 25 mg/m2 per day x
5 CIV...D1-5
(Total Dose 125 mg/m2)
FLUOROURACIL [5-FU] 800 mg/m2 per day x
5 CIV...D2-6
(Total Dose 4000 mg/m2)
LEUCOVORIN [Leu] 500 mg/m2 per day x
6 CIV...D1-6
(Total Dose 3000 mg/m2)
CYCLE: 28 days
REFER: Dreyfuss AI, et al: ANN INTERN MED 1990; 112:167-172.
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