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DoseCalc OnLine
spacer Guide To Oncology Regimens

DISEASE: Gastric or Small Bowel

Select a REGIMEN:

EAP
EFP
FAM






DISEASE: Gastric or Small Bowel

REGIMEN: EAP

    ETOPOSIDE [VP-16] 120 mg/m2 per day IV...D4,5,6

    DOXORUBICIN [DOX] 20 mg/m2 IV...D1,7
    Caution: Monitor cumulative dose (cardiac toxicity)

    CISPLATIN [CDDP] 40 mg/m2 IV over 2 hrs...D2,8

CYCLE: 21-28 days
REFER: Preusser P, et al: J CLIN ONCOL 1989; 7:1310-1317.




DISEASE: Gastric or Small Bowel

REGIMEN: EFP

    FLUOROURACIL [5-FU] 900 mg/m2 per day x 5 CIV...D1-5
    (Total Dose 4500 mg)

    CISPLATIN [CDDP] 20 mg/m2 per day x 5 IV...D1-5 ETOPOSIDE [VP-16] 90 mg/m2 IV/2 hrs...D1,3,5

CYCLE: 24-28 days
REFER: Ajani J, et al: Sixth Intern. Conf. on the Adjuvant Therapy of Cancer, Proc. & Abstracts 1990; 396-404.




DISEASE: Gastric or Small Bowel

REGIMEN: FAM

    FLUOROURACIL [5-FU] 600 mg/m2 IV...D1,8,29,36

    DOXORUBICIN [DOX] 30 mg/m2 IV...D1,29
    Caution: Monitor cumulative dose (cardiac toxicity)

    MITOMYCIN-C [MITC] 10 mg/m2 IV...D1
    Caution: Monitor cumulative dose (marrow toxicity, hemolytic uremic syndrome)

CYCLE: 8 weeks
REFER: MacDonald JS, et al: ANN INTERN MED 1980; 93:533-536.




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