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DISEASE: Breast
Select a REGIMEN:
CAF/IV
CAF PO
CMF IV
CNF PO
CMFP
CNF
FAC
FAC (Bolus)
MF
MV
VATH
PACLITAXEL
DISEASE: Breast
REGIMEN: CAF/IV
-
CYCLOPHOSPHAMIDE [CTX] 500 mg/m2 IV...D1
DOXORUBICIN [DOX] 50 mg/m2 IV... D1
Caution: Monitor cumulative dose (cardiac toxicity)
FLUOROURACIL [5-FU] 500 mg/m2 IV...D1
CYCLE: 21 days
REFER: Smalley RV, et al: A Southeastern Cancer Study Grp Prj:
CANCER 1977; 40:625-632.
DISEASE:Breast
REGIMEN: CAF/PO
-
CYCLOPHOSPHAMIDE[CTX] 100 mg/m2 per day PO...D1-14
DOXORUBICIN [DOX] 30 mg/m2 IV
Caution: Monitor cumulative dose (cardiac toxicity)
FLUOROURACIL [5-FU] 500 mg/m2 IV...D1,8
CYCLE: 28 days
REFER: Skeel RT: Handbook of Cancer Chemotherapy, 3rd Ed.
Little, Brown & Co. 1991
DISEASE: Breast
REGIMEN: CMF/IV
-
CYCLOPHOSPHAMIDE [CTX] 600 mg/m2 IV...D1
METHOTREXATE [MTX] 40 mg/m2 IV... D1
FLUOROURACIL [5-FU] 600 mg/m2 IV... D1
CYCLE: 21 days
REFER: Weiss RB, et al: AM J MED 1987; 83:455-463.
DISEASE: Breast
REGIMEN: CMF/PO
-
CYCLOPHOSPHAMIDE [CTX] 100 mg/m2 per day PO...
D1-14
METHOTREXATE [MTX] 30 - 40 mg/m2
IV...D1,8
Lower dose > 65 yrs of age
FLUOROURACIL [5-FU] 400 - 600 mg/m2
IV...D1,8
Lower dose > 65 yrs of age
CYCLE: 28 days
REFER: Bonadonna G, et al: NEJM 1976; 294:405-410.
DISEASE: Breast
REGIMEN: CMFP
-
CYCLOPHOSPHAMIDE [CTX] 100 mg/m2 per day
PO...D1-14
METHOTREXATE [MTX] 30 - 40 mg/m2 IV....D1,8
Lower dose >65 years of age
FLUOROURACIL [5-FU] 400 - 600 mg/m2 IV...D1,8
Lower dose >65 years of age
PREDNISONE [Pred] 40 mg/m2 per day PO... D1-14
CYCLE: 28 days
REFER: Marschke RF, et al: CANCER 1989; 63:1931-1937.
DISEASE: Breast
REGIMEN: CNF
-
CYCLOPHOSPHAMIDE [CTX] 500 mg/m2 IV... D1
MITOXANTRONE [DHAD] 10 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)
FLUOROURACIL [5-FU] 500 mg/m2 IV...D1
CYCLE: 21 days
REFER: Bennett JM, et al: J CLIN ONCOL 1988; 6:1611-1620.
DISEASE: Breast
REGIMEN: FAC
-
FLUOROURACIL [5-FU] 500 mg/m2 IV...D1,5
DOXORUBICIN [DOX] 50 mg/m2 CIV over
48-96 hrs D1
Caution: Monitor cumulative dose (cardiac toxicity)
CYCLOPHOSPHAMIDE [CTX] 500 mg/m2 IV...D1
CYCLE: 21 days
REFER: Hortobagyi GH, et al: CANCER 1989; 63:37-45.
DISEASE: Breast
REGIMEN: FAC (Bolus)
-
FLUOROURACIL [5-FU] 500 mg/m2 IV... D1,8
DOXORUBICIN [DOX] 50 mg/m2 IV...D1
Caution: Monitor cumulative dose (cardiac toxicity)
CYCLOPHOSPHAMIDE [CTX] 500 mg/m2 IV... D1
REFER: Blumenschein G, et al: PROC ASCO 1974; 15:193.
DISEASE: Breast
REGIMEN: MF
-
METHOTREXATE [MTX] 100 mg/m2 IV...D1,8
FLUOROURACIL [5-FU] 600 mg/m2 IV...D1,8
given 1 hr after MTX
LEUCOVORIN [Leu] 10 mg/m2 IV/PO
q 6 hrs x 6, starting 24 hrs after MTX
CYCLE: 4 weeks
DISEASE: Breast
REGIMEN: MV
-
MITOMYCIN C [MITC] 20 mg/m2 IV... D1
Caution: Monitor cumulative dose (marrow toxicity, hemolytic uremic syndrome)
VINBLASTINE [VLB] .15mg/kg IV...D1, 21
CYCLE: 6-8 weeks
REFER: Konits PH, et al: CANCER 1981; 48:1295-1298
DISEASE: Breast
REGIMEN: VATH
-
VINBLASTINE [VLB] 4.5 mg/m2 IV...D1
DOXORUBICIN [DOX] 45 mg/m2 IV... D1
THIOTEPA [TSPA] 12MG/M2 IV...D1
FLUOXYMESTERONE [HALO] 30 mg per day PO... D1-21
CYCLE: 21 days
DISEASE: Breast
REGIMEN: PACLITAXEL
-
PACLITAXEL [TAX] 175 mg/m2 CI over 3
hrs ...D1
CYCLE: 21 days
REFER: TAXOL(R) (paclitaxel) Bristol-Myers Squibb Co, prescribing info
in PHYSICIANS DESK REFERENCE 49th Ed. Montvale, NJ; 1995;682.
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