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DoseCalc OnLine
spacer Guide To Oncology Regimens

DISEASE: Brain

Select a REGIMEN:

BCNU
PCV
PROC





DISEASE: Brain

REGIMEN: BCNU

    CARMUSTINE [BCNU] 80 mg/m2 per day IV...D1-3
    Caution: Monitor cumulative dose (pulmonary and marrow toxicity)

CYCLE: 6-8 wks
REFER: Walker MD, et al: J NEUROSURG 1978; 49:333-343.




DISEASE: Brain

REGIMEN: PCV

    LOMUSTINE [CCNU] 110 mg/m2 PO...D1
    Caution: Monitor cumulative dose (pulmonary and marrow toxicity)

    PROCARBAZINE [PCB] 60 mg/m2 per day PO...D8-21

    VINCRISTINE [VCR] 1.4 mg/m2 IV...D8, 2
    Maximum dose is 2 mg

CYCLE: 6-8 weeks
REFER: Levin VA, et al: INT J RADIAT ONCOL BIOL PHYS 1990; 18:321-324.





DISEASE: Brain

REGIMEN: PROC

    PROCARBAZINE [PCB] 150 mg/m2 per day PO...D1-28
    divided into 3-4 doses per day

CYCLE: 8 weeks
REFER: Green SB, et al: CA TREAT REP 1983; 67:121-132.






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