DoseCalc Measurement Formulas

Body Surface Area (in meters squared )

BSA = 0.007184 x [Weight in kg] to power 0.425 x [Height in cm] to power 0.725

(Dubois, Arch Intern Med 1916; 17:863-871)

Ideal Body Weight [in kg]

For Males
IBW = 51.65 + 1.85 x ([Height in inches] - 60)

For Females
IBW = 48.67 + 1.65 x ([Height in inches] - 60)

(Am J Hosp Pharm 1983; 40(6):1016-1019)

Basic Energy Expenditure [in KCal/day]

For Males
BEE = 66 + 13.7 x [Weight in kg] + 5.0 x [Height in cm] - 6.8 x Age

For Females
BEE = 655 + 9.6 x [Weight in kg] + 1.8 x [Height in cm] - 4.7 x Age

(Wilson JD, et al: Harrison's Principles of Internal Medicine, 12th Ed. McGraw-Hill 1991; 430)

Absolute Neutrophil Count [in K/mm3]

ANC = [WBC in K/mm3] x ( [PMN in %] + [Bands in %] ) / 100

Estimated Creatinine Clearance [in cc/min]

For Males
CCr = [Weight in kg] x ( 140 - Age ) / (72 x SerumCreatinine)

For Females
CCr = [Male Est CCr] x 0.85
Serum Creatinine measured in mg/dL

(Cockroft DW, Gault MH: NEPHRON 1976; 16:31-41)

Measured Creatinine Clearance (in cc/min]

CCr = (UrineCreatinine x UrineVolume)/(1440 x SerumCreatinine)

Serum Creatinine measured in mg/dL
Urine Creatinine measured in mg/dL
Urine Volume measured in mL/24 hrs

(Comstock,TJ. Pharmaco Therapy; Elsevier 1992:645-659)

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